About HPBLUP

HPBLUP is a modern genetic evaluation system for any animal or plant breeding application.

HPBLUP is easy to use, fast, suitable for simultaneous analysis of a large number of traits and able to fit complex models. It supports a wide range of methods to specify genetic similarity between individuals, such as pedigree relationships, genomic relationships, and regression on SNP genotypes.

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Availability

The HPBLUP software can be downloaded from this website. A 30-days free trial license is available for evaluation purposes. A trial license allows you to do a full run, regardless of the number of equations, to be able to evaluate its performance. A commercial license is available for routine use. For evaluation centers providing genetic evaluations as a commercial service, there are separate licenses available.

Advantages

HPBLUP allows you to use sophisticated models in estimation of breeding values for any species. HPBLUP uses a fast, state-of-the-art solving algorithm. This ensures fast computation of predicted genetic merit even if your evaluation model is complex and your population is large. HPBLUP can be used in practice for modern applications, such as random regression models and social interaction models. Genetic similarity between individuals or inbred lines can be specified with pedigree and genomic information. HPBLUP contains tools to improve the design of the genetic evaluation and verify that it works correctly.

Origin

HPBLUP builds on 15 years of experience of developing MiXBLUP. Unlike MiXBLUP, HPBLUP does not contain any software components that are developed by LUKE National Resources Institute Finland.

Support

The user license includes support for installing the software and for software related problems. Extensive documentation on HPBLUP is available on this site. For an additional service fee also individual support is available for any issues related to setting up a fully operational genetic evaluation.

Features

  • Fast
  • Accessible for relatively inexperienced users
  • Suits diploid and polyploid species
  • Handles large populations
  • User friendly interface
  • Meaningful default settings
  • HPBLUP does not require other software to be installed
  • Full functionality available on Linux platforms
  • Not yet available on Windows platforms
  • Includes professional support

Possibilities

  • Data and pedigree may contain numerical as well as alphanumerical data
  • All common formats of genomic information are supported
  • Large datasets
  • Large number of traits
  • Large number of fixed and random effects
  • Individuals with unknown parents can be grouped into a single base population, or in multiple either related or unrelated base populations
  • Indirect genetic effects can be fitted: e.g. maternal or social genetic effects
  • Random regression or reaction norm models
  • Social interaction models
  • Trait-specific models
  • Support for non-additive genetic effects like dominance or epistasis
  • Old solutions can be used as starting values or prior information to accelerate genetic evaluations
  • Multiple genetic and non-genetic random effects with correlated level effects
  • Full support for exact or approximate multi-trait genome-wide association study (GWAS) from the full data
  • User-friendly interface to do a range of validation studies